Cornell's study of horses provides insight into human flu pandemic

Stored safely in a freezer at Cornell's James A. Baker Institute for Animal Health are samples of the virus thought to be most like the one public health experts expect someday to afflict record numbers of the world's population. The virus was collected in 1973 during an outbreak of equine influenza at a Florida racetrack. Dorothy Holmes, an infectious disease specialist in Cornell's College of Veterinary Medicine, had obtained samples of the virus with the intention of using it to create nasal spray vaccines for horses.

Now, 35 years later, Cornell scientists have the rare chance to study the behavior of the organism to figure out why this particular virus, an H7 serotype, outperforms all other serotypes in its lethal powers. The study is supported by a seven-year, $3 million award from the National Institutes of Health.

"Influenza H7 is unique in its capability to invade not only the lungs but other parts of the host's body, including the brain, and this is why it's so dangerous," explains Gary Whittaker, an associate professor of virology who leads the project.

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